All puppies bred by EIRAMOR WHITE SWISS SHEPHERDS are produced by FULL DNA breed profiled parents
MDR1
MDR1 is a MULTI DRUG SENSITIVITY eg: herding breeds can have severe adverse reactions to the antiparasitic drug, ivermectin (used in many heartworm preventatives).
The cause is a DNA mutation in the dogs multi-drug resistance gene (MDR1 gene). The MDR1 gene protects the brain and plays the vital role in drug elimination.
Dogs affected are unable to remove drugs and other toxins from the brain and surrounding tissue therefore exposure to these drugs could result in serious neurological signs -blindness,ataxia,hypersalivation,tremor,respiratory disease and even death.
Dogs carrying the mutated gene MUST be bred with a normal/normal (clear) dog ; resulting puppies will not be affected.
Degenerative Myelopathy
This disease, a result of gradual loss of both myelin (the insulation around nerve fibers) and spinal cord nerve fibers which begins in the thoracic spine, causes progressive loss of coordination and weakness in the back legs which eventually leads to the dog being unable to walk. Loss of bowel and bladder control result as well. Unlike spinal cord injuries, this form of spinal paralysis is generally not painful as the nerves which would transmit the pain degenerate.
The disease results in hind limb paralysis over time and there is no recognized effective treatment for affected dogs.
von Willebrand’s Disease
von Willebrand's disease is probably the most common inherited bleeding disorder in dogs. It is caused by lack of von Willebrand factor which is a protein that plays a key role in the blood clotting process resulting in prolonged bleeding. The disorder occurs in varying degrees of severity ranging from trivial bleeding to excessive life threatening haemorrhages.
Symptoms include spontaneous bleeding from the nose, gum and other mucous membranes. Excessive bleeding occurs after an injury, trauma or a surgery. Often dogs don’t show clinical signs until something starts the bleeding, such as nail trimming, teething, spaying and sterilizing etc . Bleeding also occurs internally in the stomach, intestines, urinary tracts, the genitals and / or into the joints.
Canine Hyperuricosuria
Dogs with Hyperuricosuria are most commonly present with symptoms of recurrent urinary tract inflammation, which include frequent urination ,blood in urine, straining to urinate. Also may have loss of appetite,lethargy,weakness,vomiting and pain.
Haemophilia A/factor V111
Renal Cystadenocarcinoma and Nodular Dermatofibrosis
Inherited genetic predisposition to kidney, dermal and uterine cancer in dogs. This condition manifests as a combination of abnormal masses in the kidneys and the skin of both male and female dogs and also the uterus in female dogs. Affected dogs show signs of chronic kidney disease which may include frequent urination, blood in urine, frequent drinking,depression,inappetence and weight loss.Usually present in affected dogs around 6 1/2 years of age with small , firm bumps under the surface of the skin.
Authorised Collector for Genetic Technologies - Animal Network - Collection ID S4570B